Seglentis

Generic name:celecoxib and tramadol hydrochloride
Dosage form: tablets
Drug class:Narcotic analgesic combinations

Medically reviewed by Judith Stewart, BPharm. Last updated on Oct 19, 2021.

What is Seglentis?

Seglentis is:

• A strong prescription pain medicine that contains the opioid (narcotic) tramadol and the Nonsteroidal Anti-inflammatory Drug (NSAID) celecoxib.
• Seglentis is used for the management of acute pain in adults, when other pain treatments such as non-opioid pain medicines do not treat your pain well enough or you cannot tolerate them.
• An opioid pain medicine that can put you at risk for overdose and death. Even if you take your dose correctly as prescribed you are at risk for opioid addiction, abuse, and misuse that can lead to death.

Important information

• Get emergency help or call 911 right away if you take too much Seglentis (overdose). When you first start taking Seglentis, when your dose is changed, or if you take too much (overdose), serious or life-threatening breathing problems that can lead to death may occur. Talk to your healthcare provider about naloxone, a medicine for the emergency treatment of an opioid overdose.
• Taking Seglentis with other opioid medicines, benzodiazepines, alcohol, or other central nervous system depressants (including street drugs) can cause severe drowsiness, decreased awareness, breathing problems, coma, and death.
• Never give anyone else your Seglentis. They could die from taking it. Selling or giving away Seglentis is against the law.
• Store Seglentis securely, out of sight and reach of children, and in a location not accessible by others, including visitors to the home.
• Celecoxib can cause serious side effects, including:
  • Increased risk of a heart attack or stroke that can lead to death. This risk may happen early in treatment and may increase:
    • with increasing doses of NSAIDs
    • with longer use of NSAIDs