Generic name:nefazodone [ ne-FAZ-oh-done ]
Drug class:Phenylpiperazine antidepressants
Medically reviewed by Drugs.com. Last updated on Feb 4, 2022.
The Serzone brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.
What is Serzone?
Serzone is an antidepressant medication. It affects chemicals in the brain that may become unbalanced and cause depression.
Serzone is used to relieve symptoms of depression such as feelings of sadness, worthlessness, or guilt; loss of interest in daily activities; changes in appetite; tiredness; sleeping too much; insomnia; and thoughts of death or suicide.
Serzone may also be used for purposes other than those listed in this medication guide.
Important information about Serzone?
Do not take Serzone if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days, or if you are taking terfenadine (Seldane, Seldane-D), astemizole (Hismanal), cisapride (Propulsid), pimozide (Orap), triazolam (Halcion), or carbamazepine (Tegretol, Tegretol XR, Epitol, Carbatrol).
In rare cases, treatment with Serzone has been associated with serious liver problems, sometimes resulting in liver transplant or death. Contact your doctor immediately if you experience yellowing of the skin or eyes; unusually dark urine; loss of appetite that lasts several days or longer; severe nausea; or stomach pain. These may be early signs of liver problems.
Use caution when driving, operating machinery, or performing other hazardous activities. Serzone may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.
Dizziness may be more likely to occur when you rise from a sitting or lying position. Rise slowly to prevent dizziness and a possible fall.
Avoid alcohol during treatmen...
