Sesquient Injection
Generic name:fosphenytoin sodium
Dosage form: injection, solution
Drug class:Hydantoin anticonvulsants
Medically reviewed by Drugs.com. Last updated on Nov 1, 2020.
On This Page
- Boxed Warning
- Indications and Usage
- Dosage and Administration
- Dosage Forms and Strengths
- Contraindications
- Warnings and Precautions
- Adverse Reactions/Side Effects
- Drug Interactions
- Use In Specific Populations
- Overdosage
- Description
- Clinical Pharmacology
- Nonclinical Toxicology
- Clinical Studies
- How Supplied/Storage and Handling
- Patient Counseling Information
The rate of intravenous SESQUIENT administration should not exceed 150 mg phenytoin sodium equivalents (PE) per minute in adults because of the risk of severe hypotension and cardiac arrhythmias. Careful cardiac monitoring is needed during and after administering intravenous SESQUIENT. Although the risk of cardiovascular toxicity increases with infusion rates above the recommended infusion rate, these events have also been reported at or below the recommended infusion rate. Reduction in rate of administration or discontinuation of dosing may be needed [see Warnings and Precautions (5.2) and Dosage and Administration (2.3, 2.4)].
The Sesquient brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.
Indications and Usage for Sesquient Injection
SESQUIENT is indicated:
- for the treatment of generalized tonic-clonic status epilepticus in adult patients
- for the prevention and treatment of seizures occurring during neurosurgery in adult patients.
- for short-term substitution for oral phenytoin in patients 2 years of age and older. SESQUIENT should be used only when oral phenytoin administration is not possible [see Dosage and Administration (2.4) and Warnings and Precautions (5.2)].
