Sevoflurane
Dosage form: inhalant
Drug class:General anesthetics
Medically reviewed by Drugs.com. Last updated on Jun 1, 2022.
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Sevoflurane Description
Sevoflurane, USP, a volatile liquid for inhalation, a nonflammable and nonexplosive liquid administered by vaporization, is a halogenated general inhalation anesthetic drug. Sevoflurane is fluoromethyl 2,2,2,-trifluoro-1-(trifluoromethyl) ethyl ether and its structural formula is:
Sevoflurane, Physical Constants are:
Molecular weight | 200.05 |
Boiling point at 760 mm Hg | 58.6°C |
Specific gravity at 20°C | 1.520 - 1.525 |
Vapor pressure in mm Hg | 157 mm Hg at 20°C 197 mm Hg at 25°C 317 mm Hg at 36°C |
Distribution Partition Coefficients at 37°C:
Blood/Gas | 0.63 - 0.69 |
Water/Gas | 0.36 |
Olive Oil/Gas | 47 – 54 |
Brain/Gas | 1.15 |
Mean Component/Gas Partition Coefficients at 25°C for Polymers Used Commonly in Medical Applications:
Conductive rubber | 14.0 |
Butyl rubber | 7.7 |
Polyvinylchloride | 17.4 |
Polyethylene | 1.3 |
Sevoflurane is nonflammable and nonexplosive as defined by the requirements of International Electrotechnical Commission 601-2-13.
Sevoflurane is a clear, colorless, liquid containing no additives. Sevoflurane is not corrosive to stainless steel, brass, aluminum, nickel-plated brass, chrome-plated brass or copper beryllium..
