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Silver sulfadiazine topical
  • Treatments
  • Burns
  • External

Silver sulfadiazine topical

Generic name: silver sulfadiazine topical [ SIL-ver-SUL-fa-DYE-a-zeen-TOP-ik-al ]
Brand names: Silvadene, SSD, Thermazene, SSD AF
Dosage form: topical cream (1%)
Drug class:Topical antibiotics

Medically reviewed by Drugs.com on May 25, 2022. Written by Cerner Multum.

What is silver sulfadiazine topical?

Silver sulfadiazine is an antibiotic. It fights bacteria and yeast on the skin.

Silver sulfadiazine topical (for the skin) is used to treat or prevent serious infection on areas of skin with second- or third-degree burns.

Silver sulfadiazine topical may also be used for purposes not listed in this medication guide.

Warnings

Silver sulfadiazine topical may cause serious medical problems in a newborn if you use silver sulfadiazine topical during late pregnancy (close to your delivery date). This medicine should also not be used on premature babies or any child younger than 2 months old.

Before taking this medicine

You should not use this medicine if you are allergic to silver sulfadiazine.

Silver sulfadiazine topical may cause serious medical problems in a newborn if you use this medicine during late pregnancy (close to your delivery date). This medicine should also not be used on premature babies or any child younger than 2 months old.

To make sure silver sulfadiazine topical is safe for you, tell your doctor if you have:

  • liver disease;

  • kidney disease;

  • a genetic enzyme deficiency called glucose-6-phosphate dehydrogenase (G6PD) deficiency; or

  • an allergy to sulfa drugs.

FDA pregnancy category B. Silver sulfadiazine topical is not expected to harm an unborn baby. However, this medicine can cause serious medical problems in a newborn and should not be used during late pregnancy.

It is not known whether silver sulfadiazine topical passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.

How should I use silver sulfadiazine topical?

Follow all directions on your prescription label. Do not use silver sulfadiazine topical in larger or smaller amounts or for longer than recommended.

Wash your hands before and after applying silver sulfadiazine cream.

The person applying silver sulfadiazine to burn wounds should wear sterile disposable gloves. Take care to keep the treatment area as clean as possible to prevent further infection.

Clean the area to be treated as directed by your doctor. Apply enough silver sulfadiazine to cover the affected area evenly. This medicine should be applied in a layer about one 16th (1...