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Sinemet
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Sinemet

Generic name:carbidopa and levodopaKAR-bi-DOE-pa-and-LEE-voe-DOE-pa ]
Brand names: Sinemet, Sinemet CR
Drug class:Dopaminergic antiparkinsonism agents

Medically reviewed by Philip Thornton, DipPharm. Last updated on Jun 1, 2021.

What is Sinemet?

Sinemet contains a combination of carbidopa and levodopa.

Sinemet is used to treat symptoms of Parkinson's disease, such as muscle stiffness, tremors, spasms, and poor muscle control. Parkinson's disease may be caused by low levels of a chemical called dopamine (DOE pa meen) in the brain.

Sinemet is also used to treat Parkinson symptoms caused by carbon monoxide carbon monoxide poisoning or manganese intoxication.

Warnings

You should not use Sinemet if you have narrow-angle glaucoma.

Do not use Sinemet if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, or tranylcypromine.

Before taking this medicine

You should not use Sinemet if you are allergic to carbidopa or levodopa, or if you have:

  • narrow-angle glaucoma.

Do not use Sinemet if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, tranylcypromine, and others.

To make sure Sinemet is safe for you, tell your ...