Generic name: carbidopa and levodopa (oral route) [ kar-bi-DOE-pa, lee-voe-DOE-pa ]
Drug class:Dopaminergic antiparkinsonism agents
Medically reviewed by Drugs.com. Last updated on Feb 28, 2022.
Commonly used brand name(s)
In the U.S.
- Parcopa
- Rytary
- Sinemet 10-100
- Sinemet 25-100
- Sinemet 25-250
- Sinemet CR
In Canada
- Sinemet 100/10
- Sinemet 100/25
- Sinemet 250/25
- Sinemet CR 100/25
- Sinemet CR 200/50
Available Dosage Forms:
- Tablet, Extended Release
- Tablet
- Capsule, Extended Release
- Tablet, Disintegrating
Therapeutic Class: Antiparkinsonian
Pharmacologic Class: Decarboxylase Inhibitor
Uses for Sinemet 25-250
Carbidopa and levodopa combination is used to treat Parkinson's disease, sometimes called shaking palsy or paralysis agitans. Parkinson's disease is a disorder of the central nervous system (brain and spinal cord).
Extended-release carbidopa and levodopa (Rytary®) is also used to treat parkinsonism caused by encephalitis, or parkinsonism caused by carbon monoxide or manganese poisoning.
Dopamine is a naturally occurring substance in the brain that helps provide control of movement and activities such as walking and talking. In patients with Parkinson's disease, there is not enough dopamine in some parts of the brain. Levodopa enters the brain and helps replace the missing dopamine, which allows people to function better. By increasing the amount of dopamine in the brain, levodopa helps control symptoms and helps you to perform daily activities such as dressing, walking, and handling utensils.
This medicine is available only with your doctor's prescription.
Before using Sinemet 25-250
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergi...