Sinex Nasal Spray

Generic name:phenylephrine nasal [ FEN-il-EFF-rin ]
Brand names: 4-Way, Afrin 4 Hour Extra Moisturizing, Little Noses Decongestant, Nasal Four, Neo-Synephrine Nasal, Sinex Nasal Spray
Drug class:Nasal antihistamines and decongestants

Medically reviewed by Drugs.com on Jan 31, 2022. Written by Cerner Multum.

What is Sinex Nasal Spray?

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

Sinex Nasal Spray is used to treat nasal congestion and sinus pressure caused by allergies, the common cold, or the flu. Phenylephrine may be used to treat congestion of the tubes that drain fluid from your inner ears, called the eustachian (yoo-STAY-shun) tubes.

Sinex Nasal Spray may also be used for purposes not listed in this medication guide.

Warnings

Do not use Sinex Nasal Spray if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.

Before taking this medicine

You should not use Sinex Nasal Spray if you are allergic to it.

Do not use Sinex Nasal Spray if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

Ask a doctor or pharmacist if it is safe for you to use this medicine if you have other medical conditions, especially:

• heart disease, heart rhythm disorder;

• high blood pressure;

• diabetes;

• glaucoma;

• a thyroid disorder; or

• an enlarged prostate or urination problems.

It is not known whether Sinex Nasal Spray will harm an unborn baby. Do not use this medicine without a doctor's advice if you are pregnant.

It is not known whether