Sirolimus (Topical application)
Medically reviewed by Drugs.com. Last updated on Apr 4, 2022.
Commonly used brand name(s)
In the U.S.
- Hyftor
Uses for sirolimus
Sirolimus topical gel is used to treat facial angiofibroma (type of noncancerous tumor) caused by a genetic condition called tuberous sclerosis.
Sirolimus is available only with your doctor's prescription.
Before using sirolimus
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For sirolimus, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to sirolimus or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies have not been performed on the relationship of age to the effects of sirolimus topical gel in children younger than 6 years of age. Safety and efficacy have not been established.
Geriatric
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of sirolimus topical gel in the elderly.
Breastfeeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking sirolimus, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using sirolimus with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
- Levoketoconazole
- Mifepristone
- Posaconazole
- Ritonavir
- Voriconazole
Using sirolimus with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Adenovirus Vaccine Type 4, Live
- Adenovirus Vaccine Type 7, Live
- Alefacept
- Amiodarone
- Asciminib
- Avacopan
- Bacillus of Calmette and Guerin Vaccine, Live
- Belzutifan
- Benazepril
- Berotralstat
- Boceprevir
- Cannabidiol
- Capmatinib
- Captopril
- Ceritinib
- Clarithromycin
- Cobicistat
- Conivaptan
- Crizotinib
- Dengue Tetravalent Vaccine, Live
- Duvelisib
- Efavirenz
- Eluxadoline
- Enalapril
- Enalaprilat
- Enzalutamide
- Erdafitinib
- Etravirine
- Fedratinib
- Fexinidazole
- Fluconazole
- Fo...
