Sodium picosulfate, magnesium, and citric acid (Oral)

Medically reviewed by Drugs.com. Last updated on Jun 8, 2022.

Commonly used brand name(s)

In the U.S.

• Clenpiq
• Prepopik

Available Dosage Forms:

• Solution

Therapeutic Class: Laxative, Stimulant Combination

Uses for sodium picosulfate, magnesium, and citric acid

Citric acid, magnesium oxide, and sodium picosulfate combination is used to cleanse the colon (bowel) in preparation for a procedure called colonoscopy. Sodium picosulfate, magnesium, and citric acid is a laxative. It works by causing you to have diarrhea to clean your colon. Cleaning your colon will help your doctor see inside of it more clearly during colonoscopy.

Sodium picosulfate, magnesium, and citric acid is available only with your doctor's prescription.

Before using sodium picosulfate, magnesium, and citric acid

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For sodium picosulfate, magnesium, and citric acid, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to sodium picosulfate, magnesium, and citric acid or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of Clenpiq® and Prepopik® in children younger than 9 years of age. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of citric acid, magnesium oxide, and sodium picosulfate combination in the elderly. However, elderly patients are more likely to have age-related liver, kidney, or heart problems, and unwanted effects (eg, fluid or electrolyte imbalance), which may require caution in patients receiving sodium picosulfate, magnesium, and citric acid.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking sodium picosulfate, magnesium, and citric acid, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using sodium picosulfate, magnesium, and citric acid with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Aclidinium
• Amantadine
• Amiloride
• Amitriptyline
• Amoxapine
• Anisotropine
...