Sofosbuvir and velpatasvir
Generic name: sofosbuvir and velpatasvir [ soe-FOS-bue-vir-and-vel-PAT-as-vir ]
Brand name: Epclusa
Dosage forms: oral pellet (150 mg-37.5 mg; 200 mg-50 mg); oral tablet (200 mg-50 mg; 400 mg-100 mg)
Drug class:Antiviral combinations
What is sofosbuvir and velpatasvir?
Sofosbuvir and velpatasvir is a combination antiviral medicine used to treat chronic hepatitis C in adults and children at least 3 years old.
Sofosbuvir and velpatasvir treats specific genotypes of hepatitis C, and only in certain people. Your doctor will perform tests to make sure sofosbuvir and velpatasvir is the right treatment for you.
Sofosbuvir and velpatasvir is sometimes used in people who also have HIV, but sofosbuvir and velpatasvir does not treat HIV or AIDS.
Sofosbuvir and velpatasvir may also be used for purposes not listed in this medication guide.
Warnings
If you've had hepatitis B, it may come back or get worse. Call your doctor if you don't feel well and you have right-sided upper stomach pain, vomiting, loss of appetite, or yellowing of your skin or eyes.
Before taking this medicine
sofosbuvir and velpatasvir is sometimes used in combination with other antiviral medication. Read the medication guide or patient instructions provided with each medication in your combination therapy.
When taking sofosbuvir and velpatasvir with other medicine: Tell your doctor about all your medical conditions, and if you are pregnant or breastfeeding.
Tell your doctor if you have ever had:
hepatitis B;
liver problems other than hepatitis C;
kidney disease (or if you are on dialysis);
diabetes;
HIV (human immunodeficiency virus); or
if you use a blood thinner (warfarin, Coumadin, Jantoven) and you have routine "INR" or prothrombin time tests.
Sofosbuvir and velpatasvir is sometimes used in combination with ribavirin. Both men and women using ribavirin should use birth control to prevent pregnancy. Ribavirin can harm an unborn baby if the mother or father is using ribavirin. Keep using birth control for at least 6 months after your last dose of ribavirin. Tell your doctor right away if a pregnancy occurs.
Ask a doctor if it is safe to breastfeed while using these medicines.
How should I take sofosbuvir and velpatasvir?
Follow all directions on your prescrip...
