Sofosbuvir, velpatasvir, and voxilaprevir
Generic name: sofosbuvir, velpatasvir, and voxilaprevir [ soe-FOS-bue-vir, vel-PAT-as-vir, and-VOX-i-LA-pre-vir ]
Brand name: Vosevi
Dosage form: oral tablet (400 mg-100 mg-100 mg)
Drug class:Antiviral combinations
What is sofosbuvir, velpatasvir, and voxilaprevir (Vosevi)?
Sofosbuvir, velpatasvir, and voxilaprevir (Vosevi) is a combination antiviral medicine that is used to treat chronic hepatitis C in adults.
Vosevi treats specific genotypes of hepatitis C, and only in certain people. Use only the medications prescribed for you. Do not share your medicine with other people.
Vosevi is sometimes used in people who also have HIV. Vosevi is not a treatment for HIV or AIDS.
Vosevi may also be used for purposes not listed in this medication guide.
Warnings
If you have ever had hepatitis B, sofosbuvir, velpatasvir, and voxilaprevir can cause the condition to come back or get worse. You will need frequent blood tests to check your liver function.
Sofosbuvir, velpatasvir, and voxilaprevir is sometimes used in combination with other medication. Read the medication guide or patient instructions provided with each medication in your combination therapy.
Before taking this medicine
You should not use this medicine if you are allergic to sofosbuvir, velpatasvir, or voxilaprevir.
Tell your doctor if you have ever had:
hepatitis B;
liver problems other than hepatitis C;
kidney disease (or if you are on dialysis); or
if you use a blood thinner (warfarin, Coumadin, Jantoven) and you have routine "INR" or prothrombin time tests.
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.
How should I take Vosevi?
Your doctor will perform blood tests to make sure you do not have conditions that would prevent you from safely using sofosbuvir, velpatasvir, and voxilaprevir.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Vosevi is usually taken once per day for 12 weeks.
Take this medicine with food, at the same time each day.
You will need frequent blood tests to check your liver function.
If you've ever had hepatitis B, using Vosevi can cause this virus to become active or get worse. You may need frequent liver function tests while us...