Solesta

Generic name:dextranomer and sodium hyaluronate [ dex-TRAN-o-mer-and-SOE-dee-um-HYE-al-ure-ON-ate ]

Medically reviewed by Drugs.com on Jan 4, 2022. Written by Cerner Multum.

What is Solesta?

Solesta are natural materials formed into a gel that is similar to certain substances that occur naturally in your body. Solesta works by thickening the tissues in your anal canal.

Solesta is injected as an implant into your anal canal to treat fecal incontinence (loss of bowel control) in adults.

This medicine is usually given after diet changes and other medications have been tried without success.

Solesta may also be used for purposes not listed in this medication guide.

Warnings

You should not receive this medicine if you have: rectal infection or bleeding, rectal fissure, rectal tumor, rectal malformation, rectal prolapse, an abnormal passageway between the rectum and vagina, stenosis (narrowing) of your anal canal, a rectal or anal implant (other than Solesta), congested blood vessels in the anus or rectum, inflammatory bowel disease, a history of radiation to your pelvic area, or a weak immune system.

Before taking this medicine

You should not receive Solesta if you are allergic to dextranomer or sodium hyaluronate, or if you have:

• rectal infection, rectal bleeding or inflammation;

• a rectal fissure, rectal tumor, or genetic malformation of your rectum;

• a prolapsed rectum;

• an abnormal passageway between the rectum and the vagina;

• a narrowing (stenosis) of your anal canal;

• any type of implant (other than Solesta) in your anus or rectum;

• congested blood vessels in the anus or rectum;

• active inflammatory bowel disease;

• a history of radiation to your pelvic area; or

• a weak immune system (caused by disease or by using certain medicine).

To make sure Solesta is safe for you, tell your doctor if you have:

• an enlarged prostate;

• long-term rectal pain;

• a bleeding or blood clotting disorder such as hemophilia;

• a history of rectal or intestinal surgery, or hemorrhoid repair; or

• if you are pregnant or breast-feeding.

How is Solesta given?

A healthcare provider will give you this medicine in an outpatient clinic setting. Solesta is given as a set of 4 injections directly into the tissues of your anal canal.

You will be given an enema to clean out your rectum just before Solesta is injected.

You will receive the injection...