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Atropine and diphenoxylate
  • Treatments
  • Diarrhea

Atropine and diphenoxylate

Generic name: atropine and diphenoxylate [ A-troe-peen-and-DYE-fen-OX-i-late ]
Brand names: Lomotil, Lonox, Lomocot, Vi-Atro
Dosage forms: oral liquid (0.025 mg-2.5 mg/5 mL); oral tablet (0.025 mg-2.5 mg)
Drug class:Antidiarrheals

Medically reviewed by Drugs.com on Mar 4, 2022. Written by Cerner Multum.

What is atropine and diphenoxylate?

Atropine affects the body in many different ways, such as reducing spasms in the bladder, stomach, and intestines.

Diphenoxylate is an antidiarrheal medication.

Atropine and diphenoxylate is a combination medicine used to treat diarrhea in adults and children who are at least 13 years old.

Atropine and diphenoxylate may also be used for purposes not listed in this medication guide.

Warnings

Do not use atropine and diphenoxylate if you have diarrhea that is caused by bacteria or by taking an antibiotic. You should not use atropine and diphenoxylate if you have a bile duct disorder causing jaundice (yellowing of your skin or eyes).

Keep this medicine where a child cannot reach it. An overdose can be fatal to a child.

Before taking this medicine

You should not use this medicine if you are allergic to atropine or diphenoxylate, or if you have:

  • obstructive jaundice (a bile duct disorder that may cause yellowing of your skin or eyes);

  • diarrhea that is caused by bacteria; or

  • diarrhea caused by using antibiotic medication.

Atropine and diphenoxylate is not approved for use by anyone younger than 6 ye...