Atropine and pralidoxime
Generic name: atropine and pralidoxime [ AT-roe-peen-and-PRAL-i-DOX-eem ]
Brand names: ATNAA, DuoDote
Dosage form: intramuscular solution (2.1 mg/0.7 mL-600 mg/2 mL)
Drug class:Antidotes
What is atropine and pralidoxime?
Atropine and pralidoxime is a combination medicine used as an antidote to treat poisoning by a pesticide (insect spray) or a chemical that interferes with the central nervous system, such as nerve gas.
atropine and pralidoxime is not effective as an antidote for all types of pesticide poisonings. You may need medications or additional treatments.
Atropine and pralidoxime may also be used for purposes not listed in this medication guide.
Warnings
In an emergency, you may not be able to tell caregivers about your health conditions. Make sure any doctor caring for you afterward knows you received this medicine.
Before taking this medicine
If possible, before you receive atropine and pralidoxime, tell your doctor if you have ever had:
an allergy to any medication;
heart problems, a heart attack or stroke;
liver or kidney disease;
asthma, COPD (chronic obstructive pulmonary disorder), or other breathing problem;
glaucoma; or
urination problems.
In an emergency situation it may not be possible to tell your caregivers if you are pregnant or breast-feeding. Make sure any doctor caring for your pregnancy or your baby knows you have received atropine and pralidoxime.
How is atropine and pralidoxime given?
Atropine and pralidoxime is injected into a muscle in your upper thigh. A healthcare provider will give you this injection.
Atropine and pralidoxime is usually given as soon as possible after the onset of poisoning symptoms. If you still have symptoms after 10 to 15 minutes, you will receive 2 more injections.
Your breathing, blood pressure, oxygen levels, kidney function, and other vital signs will be watched closely.
You may be watched for up to 72 hours to make sure the medicine has been effective and you no longer have any effects of the poison.