Somatuline Depot
Generic name:lanreotide [ lan-REE-oh-tide ]
Drug class:Somatostatin and somatostatin analogs
What is Somatuline Depo?
Somatuline Depot (lanreotide) is a man-made protein similar to a hormone in the body called somatostatin. Lanreotide lowers many substances in the body such as insulin and glucagon (involved in regulating blood sugar), growth hormone, and chemicals that affect digestion.
Somatuline Depo is used in adults to treat:
acromegaly that cannot be treated with surgery or radiation;
a certain type of pancreatic or digestive tract tumor that may spread to other parts of the body.
Somatuline Depo is sometimes given after other treatments have failed.
Warnings
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
Especially tell your healthcare provider if you take:
insulin or other diabetes medicines
cyclosporine (Gengraf, Neoral, or Sandimmune)
medicines that lower your heart rate such as beta blockers
Before taking this medicine
You should not use Somatuline Depo if you are allergic to lanreotide.
To make sure Somatuline Depot is safe for you, tell your doctor if you have ever had:
diabetes (your diabetes medicine may need to be adjusted);
liver or kidney disease;
heart disease; or
a thyroid disorder.
It is not known whether lanreotide will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
Somatuline Depo may affect fertility (your ability to have children) in women.
You should not breast-feed while using Somatuline Depo and for at least 6 months after your last dose.
How is Somatuline Depo given?
Somatuline Depo is injected under the skin.
A healthcare provider will give you this injection.
Somatuline Depo is usually given once every 4 weeks. Your doctor may occasionally change how often you receive injections.
Call your doctor if your symptoms do not improve, or if they get worse.
Your blood sugar may need to be checked often, and you may need other blood tests at your doctor's office.
Dosing information
Usual Adult Dose for Acromegaly:
Initial dose: 90 mg, by deep subcutaneous injection, every 4 weeks for 3 months
Comments:
-The goal of treatment is to reduce growth hormone (GH) and
