Sotorasib
Generic name: sotorasib [ soe-TOR-a-sib ]
Brand name: Lumakras
Dosage form: oral tablet (120 mg)
Drug class:Miscellaneous antineoplastics
What is sotorasib?
Sotorasib is used to treat non-small cell lung cancer that is advanced or has spread to other parts of the body (metastatic) after treatment with at least one cancer medicine.
Your doctor will make sure you have the correct tumor type to be treated with sotorasib.
Sotorasib may also be used for purposes not listed in this medication guide.
Warnings
Follow all directions on the label and package. Use exactly as directed.
Before taking this medicine
Tell your doctor if you have ever had:
liver disease; or
breathing problems other than lung cancer.
It is not known if sotorasib will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
Do not breastfeed while using sotorasib, and for at least 1 week after your last dose.
How should I take sotorasib?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Take the medicine at the same time each day, with or without food.
You may need to use up to 8 tablets for your entire dose. Follow your doctor's dosing instructions very carefully.
Swallow the tablet whole and do not crush, chew, or break it.
If you cannot swallow a tablet whole, place it into a glass with 4 ounces of plain water. Stir until the tablet is dispersed (it will not dissolve completely) and drink this mixture right away or stir it again and drink it within 2 hours. Do not chew the tablet pieces. Add 4 ounces more water to the glass, swirl gently and drink right away.
If you vomit shortly after taking sotorasib, do not take another dose. Take your next dose as scheduled.
You will need frequent blood tests to check your liver function. Your dose or medication schedule may be changed based on the results.
Store at room temperature away from moisture and heat.
What happens if I miss a dose?
Use the medicine as soon as you can, but skip the missed dose if you are more than 6 hours late for the dose. Do not use two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking sotorasib?
Avoid taking a stomach acid reducer, such as:
