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Subsys
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Subsys

Generic name:fentanyl (buccal/sublingual)FEN-tan-il-BUK-al-/ sub-LIN-gwal ]
Brand names: Abstral, Fentora, Subsys
Drug class:Narcotic analgesics

Medically reviewed by Philip Thornton, DipPharm. Last updated on Oct 26, 2021.

What is Subsys?

Subsys spray is an opioid pain medication. An opioid is sometimes called a narcotic.

Subsys spray is used to treat "breakthrough" cancer pain that is not controlled by other medicines. Subsys is taken together with other non-fentanyl narcotic pain medicines that are used around the clock.

Subsys is not for treating pain that is not cancer-related.

Warnings

Do not use Subsys to replace any other form of fentanyl, such as Actiq, Fentora, Onsolis, Duragesic, Lazanda, or generic brands of fentanyl (injection, skin patch, dissolving film, or "lollipop" device). Subsys is available only from a certified pharmacy under a special program. You must be registered in the program and understand the risks and benefits of taking this medication.

Do not use Subsys spray unless you are already being treated with a similar opioid pain medicine and your body is tolerant to it. Talk with your doctor if you are not sure you are opioid-tolerant.

Subsys is not for treating pain that is not cancer-related, such as pain from surgery or dental work, migraine headaches, or back pain.

Fentanyl can slow or stop your breathing, especially when you start using this medicine or whenever your dose is changed. Never take Subsys in larger amounts, or for longer than prescribed.

Some medicines can interact with fentanyl and worsen the effects on your breathing. Before using this medicine, tell your doctor if you are taking an antibiotic or any medicines to treat high blood pressure, heart rhythm disorders, depression, or viral infections such as hepatitis, HIV or AIDS.

Fatal side effects can occur if you use this medicine with...