Sudafed PSE
Generic name: naproxen and pseudoephedrine [ na-PROX-en-and-soo-doe-e-FED-rin ]
Brand names: Aleve Cold and Sinus, Aleve Sinus & Headache, Aleve-D Sinus & Cold, Sudafed PSE
Drug class:Upper respiratory combinations
What is Sudafed PSE?
Naproxen is a nonsteroidal anti-inflammatory drug (NSAID). Pseudoephedrine is a decongestant.
Sudafed PSE is a combination medicine used to treat stuffy nose, sinus congestion, headache, fever, and minor aches and pains caused by the common cold or flu.
Sudafed PSE may also be used for purposes not listed in this medication guide.
Warnings
Naproxen can increase your risk of fatal heart attack or stroke. Do not use Sudafed PSE just before or after heart bypass surgery (coronary artery bypass graft, or CABG). Naproxen may also cause stomach or intestinal bleeding, which can be fatal.
Before taking this medicine
Naproxen can increase your risk of fatal heart attack or stroke, even if you don't have any risk factors. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG).
Naproxen may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using naproxen, especially in older adults.
You should not use this medicine if you are allergic to naproxen or pseudoephedrine, or if you have ever had an asthma attack or severe allergic reaction after taking aspirin or an NSAID.
Do not use Sudafed PSE if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, tranylcypromine, and others.
Ask a doctor or pharmacist if this medicine is safe to use if you have:
heart disease, high blood pressure, diabetes;
a heart attack or stroke;
a stomach ulcer or bleeding;
asthma;
a thyroid disorder;