Sulconazole

Class: Azoles
ATC Class: D01AC09
VA Class: DE102
Chemical Name: (±)-1-[2-[[(4-Chlorophenyl)methyl]thio]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole mononitrate
Molecular Formula: C₁₈H₁₅C_l3N₂S•HNO₃
CAS Number: 61318-91-0
Brands: Exelderm

Medically reviewed by Drugs.com on Jun 21, 2021. Written by ASHP.

Introduction

Antifungal; azole (imidazole derivative).

Uses for Sulconazole

Dermatophytoses

Treatment of tinea corporis (body ringworm) and tinea cruris (jock itch) caused by Epidermophyton floccosum, Microsporum canis, Trichophyton mentagrophytes, or T. rubrum.

Treatment of tinea pedis (athlete’s foot) caused by E. floccosum, M. canis, T. mentagrophytes, or T. rubrum.

Topical antifungals usually effective for treatment of uncomplicated tinea corporis or tinea cruris. An oral antifungal may be necessary when tinea corporis or tinea cruris is extensive, dermatophyte folliculitis is present, infection does not respond to topical therapy, or patient is immunocompromised because of coexisting disease or concomitant therapy.

Topical antifungals usually effective for treatment of uncomplicated tinea pedis. An oral antifungal may be necessary for treatment of hyperkeratotic areas on the soles, for chronic moccasin-type (dry-type) tinea pedis, and for tinea unguium (fingernail or toenail dermatophyte infections, onychomycosis).

Pityriasis (Tinea) Versicolor

Treatment of pityriasis (tinea) versicolor caused by Malassezia furfur (Pityrosporum orbiculare or P. ovale).

Topical antifungals usually effective; an oral antifungal (with or without a topical antifungal) may be necessary in patients who have extensive or severe infections or failed to respond to or have frequent relapses with topical therapy.

Cutaneous Candidiasis

Treatment of cutaneous candidiasis† caused by Candida albicans.

Sulconazole Dosage and Administration

Administration

Topical Administration

Apply topically to the skin as a 1% cream or solution.

Do not apply to the eye or administer orally or intravaginally.

Apply a sufficient amount of cream or solution; rub gently into affected area and immediately surrounding healthy skin.

Dosage

Adults

Dermatophytoses

Tinea Corporis or Tinea Cruris

Apply 1% cream or solution once or twice daily for 3 weeks.

If clinical improvement does not occur after 4–6 weeks of treatment, reevaluate diagnosis.

Tinea Pedis

Apply 1% cream twice daily for 4 weeks.

If clinical improvement does not occur after 4–6 weeks of treatment, reevaluate diagnosis. Chronic moccasin-type (dry-type) tinea pedis may require 4–8 weeks or longer.

Pityriasis (Tinea) Versicolor

Topical

Apply 1% cream or solution once or twice daily for 3 weeks.

If clinical improvement does not occur af