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Sumatriptan and naproxen
  • Treatments
  • Migraine

Sumatriptan and naproxen

Generic name: naproxen and sumatriptan [ na-PROX-en-and-SOO-ma-TRIP-tan ]
Brand name: Treximet
Dosage form: oral tablet (500 mg-85 mg)
Drug class:Antimigraine agents

Medically reviewed by Drugs.com on May 11, 2022. Written by Cerner Multum.

What is naproxen and sumatriptan?

Naproxen is a nonsteroidal anti-inflammatory drug (NSAID). Sumatriptan is a migraine headache medicine.

Naproxen and sumatriptan is a combination medicine used to treat migraine headaches. sumatriptan and naproxen will only treat a headache that has already begun. It will not prevent headaches or reduce the number of attacks.

Naproxen and sumatriptan should not be used to treat cluster headaches or any headache that causes loss of movement on one side of your body.

Naproxen and sumatriptan may also be used for purposes not listed in this medication guide.

Warnings

You should not use this medicine if you have heart problems, uncontrolled high blood pressure, blood circulation problems, Wolff-Parkinson-White Syndrome, a history of heart attack or stroke, severe liver disease, a history of severe allergic reaction to aspirin or an NSAID, or if you are in late pregnancy.

Naproxen can increase your risk of fatal heart attack or stroke. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG). Naproxen may also cause stomach or intestinal bleeding, which can be fatal.

Get emergency medical help if you have signs of a heart attack or stroke: chest pain spreading to your jaw or shoulder, sudden numbness or weakness on one side of the body, slurred speech, feeling short of breath.

Do not take naproxen and sumatriptan within 24 hours before or after using another migraine headache medicine.

Before taking this medicine

You should not use sumatriptan and naproxen if you are allergic to naproxen (Aleve, Anaprox, Naprosyn) or sumatriptan (Imitrex), or if you have:

  • heart problems, uncontrolled high blood pressure;

  • a history of heart attack or stroke (including TIA or "mini-stroke");

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