Synarel
Generic name:nafarelin nasal [ NAF-a-REL-in ]
Drug class:Gonadotropin releasing hormones
What is Synarel?
Synarel (for the nose) is used to treat central precocious puberty in boys and girls. Central precocious puberty is early sexual development that occurs at or before 8 years of age in girls or 9 years of age in boys, with bone development that is advanced for the child's age.
Synarel is also used to treat endometriosis in women who are at least 18 years old.
Synarel may also be used for purposes not listed in this medication guide.
Warnings
Do not use if you are pregnant. Use effective birth control, and tell your doctor if you become pregnant.
Some children using nafarelin have had new or worsening mental problems. Call your doctor right away if your child has any unusual changes in mood or behavior (anger, aggression, crying, feeling restless or irritable).
Nafarelin may also cause seizures, especially in people who have had a seizure, epilepsy, a brain tumor, or blood vessel problems in the brain. Your risk of a seizure may also be higher if you take certain antidepressant medications.
You should not use Synarel if you have abnormal vaginal bleeding that has not been checked by a doctor.
Before taking this medicine
You should not use Synarel if you are allergic to nafarelin or similar medicines such as goserelin, leuprolide, histrelin, or triptorelin.
If you are female, you should not use Synarel if you have:
abnormal vaginal bleeding that has not been checked by a doctor; or
if you are pregnant or breastfeeding.
Tell your doctor if you have ever had:
epilepsy or other seizure disorder;
mental illness;
a tumor or blood vessel problem in your brain;
abnormal vaginal bleeding that has not been checked by a doctor;
polycystic ovary disease;
low bone mineral density;
osteoporosis (in you or a family member); or
if you smoke or drink large amounts of alcohol.
Do not use Synarel if you are pregnant. It could harm the unborn baby. You may need to have a negative pregnancy test before starting this treatment.
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