Tafasitamab
Generic name: tafasitamab [ TA-fa-SIT-a-mab ]
Brand name: Monjuvi
Dosage form: intravenous powder for injection (200 mg)
Drug class:CD19 monoclonal antibodies
What is tafasitamab?
Tafasitamab is used in combination with lenalidomide to treat diffuse large B-cell lymphoma in adults who cannot receive a stem cell transplant.
Tafasitamab is given after other cancer treatments did not work or have stopped working.
Tafasitamab was approved by the US Food and Drug Administration (FDA) on an "accelerated" basis. In clinical studies, some people responded to tafasitamab, but further studies are needed.
Tafasitamab may also be used for purposes not listed in this medication guide.
Warnings
Tafasitamab affects your immune system. You may get infections more easily, even serious or fatal infections. Call your doctor if you have signs of infection (fever, cough with mucus, chest tightness, shortness of breath, or pain or burning when you urinate).
This medicine may harm an unborn baby. Use effective birth control to prevent pregnancy while using tafasitamab and for at least 3 months after your last dose.
Carefully follow all instructions about the use of birth control while you are using tafasitamab in combination with lenalidomide.
Before taking this medicine
Tell your doctor if you have any signs of infection, or if you have recently had an infection.
Tafasitamab may harm an unborn baby. Use effective birth control to prevent pregnancy while using tafasitamab and for at least 3 months after your last dose. Tell your doctor if you become pregnant.
Tafasitamab is sometimes used in combination with lenalidomide. Both men and women using lenalidomide must use effective birth control. Even one dose can cause severe, life-threatening birth defects or death of a baby if the mother or the father is taking lenalidomide at the time of conception or during pregnancy.
Carefully follow all instructions about the use of birth control while you are using tafasitamab in combination with other medicines.
Do not breastfeed while receiving tafasitamab, and for at least 3 months after your last dose.
How is tafasitamab given?
Tafasitamab is given as an infusion into a vein. A healthcare provider will give you this injection.
Tafasitamab is given in a 28-day treatment cycle. You may need to use the medicine only on certain days of each cycle. Your doctor will determine how long to treat you with this medicine.
This medicine must be given slowly, and the infusion can take up to 2.5 hours to complete.
You may be given other medications to help prevent serious side effects or an allergic reaction. Keep using these medicines for as long a...
