Talazoparib
Generic name: talazoparib [ TAL-a-ZOE-pa-rib ]
Brand name: Talzenna
Dosage form: oral capsule (0.25 mg; 1 mg)
Drug class:PARP inhibitors
What is talazoparib?
Talazoparib is used to treat HER2-negative breast cancer that has spread to other parts of the body.
Talazoparib is used only if your cancer has a specific genetic marker (an abnormal "BRCA" gene). Your doctor will test you for this gene.
Talazoparib may also be used for purposes not listed in this medication guide.
Warnings
Using talazoparib may increase your risk of developing bone marrow problems or leukemia.
Talazoparib can lower your blood cell counts, and you may get an infection or bleed more easily. Call your doctor if you have unusual bruising or bleeding, blood in your urine or stools, weight loss, fever, weakness, tiredness, or trouble breathing.
You will need weekly or monthly blood tests, and your cancer treatments may be delayed based on the results.
Before taking this medicine
Tell your doctor if you have ever had:
kidney disease.
Using talazoparib may increase your risk of developing bone marrow problems or leukemia. Ask your doctor about this risk.
You may need to have a negative pregnancy test before starting this treatment.
Talazoparib can harm an unborn baby or cause a miscarriage if the mother or the father is using talazoparib.
If you are a woman, do not use talazoparib if you are pregnant. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 7 months after your last dose.
If you are a man, use effective birth control if your sex partner is able to get pregnant. Keep using birth control for at least 4 months after your last dose.
Tell your doctor right away if a pregnancy occurs while either the mother or the father is using talazoparib.
This medicine may affect fertility (ability to have children) in men. However, it is important to use birth control to prevent pregnancy because talazoparib can harm an unborn baby.
Do not breastfeed while using this medicine, and for at least 1 month after your last dose.
Talazoparib is not approved for use by anyone younger than 18 years old.
How should I take talazoparib?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
You may take talazoparib with or without food.
Swallow the capsule whol...
