Targiniq ER

Generic name:naloxone and oxycodone extended release tablets
Drug class:Narcotic analgesic combinations

Medically reviewed by Drugs.com. Last updated on Oct 4, 2021.

What is Targiniq ER?

Targiniq ER contains a combination of naloxone and oxycodone. Naloxone blocks certain effects of opioid medication, including feelings of well-being that can lead to opioid abuse. Oxycodone is an opioid pain medication. An opioid is sometimes called a narcotic.

Targiniq ER is used for around-the-clock treatment of severe pain, that is not controlled by other medicines. Naloxone is included in this medicine to prevent the misuse of the narcotic ingredient.

Targiniq ER is not for use on an as-needed basis for pain that is not around-the-clock.

Warnings

You should not use Targiniq ER if you have severe asthma or breathing problems, severe liver disease, or a blockage in your stomach or intestines.

Oxycodone can slow or stop your breathing. Never use this medicine in larger amounts, or for longer than prescribed. Swallow the tablet whole to avoid exposure to a potentially fatal dose. Targiniq ER may be habit-forming, even at regular doses. Never share this medicine with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.

MISUSE OF NARCOTIC MEDICINE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH, especially in a child or other person using the medicine without a prescription.

Tell your doctor if you are pregnant. Oxycodone may cause life-threatening withdrawal symptoms in a newborn if the mother has taken this medicine during pregnancy.

Some medicines can interact with naloxone and oxycodone, and cause dangerous side effects or death. Tell your doctor about all your current medicines and any you start or stop using.

Do not drink alcohol. Dangerous side effects or death could occur.

Before taking this medicine

You should not use Targiniq ER if you are allergic to naloxone or oxycodone, or if you have:

• severe asthma or breathing problems;

• severe liver disease; or

• a blockage in your stomach or intestines.

Some medicines can interact with oxycodone and cause a serious condition called serotonin syndrome. Be sure your doctor knows if you also take medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting. Ask your doctor before making any changes in how or when you take your medications.

To make sure Targiniq ER is safe for you, tell your doctor if you have:

• any type of breathing problem or lung disease;

• a history of head injury, brain tumor, or seizures;

• a history of drug abuse, alcohol addiction, or mental illness;

• urination problems;

• liver or kidney disease;

• heart disease;

• problems with your gallbladder, pancreas, or thyroid; or

• if you use a sedati...