Tazemetostat
Generic name: tazemetostat [ TAZ-e-MET-oh-stat ]
Brand name: Tazverik
Dosage form: oral tablet (200 mg)
Drug class:Miscellaneous antineoplastics
What is tazemetostat?
Tazemetostat is used to treat advanced epithelioid sarcoma, a rare slow-growing type of soft tissue cancer. tazemetostat is used when the cancer has spread to other parts of the body (metastatic) or cannot be removed with surgery.
Tazemetostat is for use in adults and children at least 16 years old.
Tazemetostat was approved by the US Food and Drug Administration (FDA) on an "accelerated" basis. In clinical studies, some people responded to this medicine, but further studies are needed.
Tazemetostat may also be used for purposes not listed in this medication guide.
Warnings
Using tazemetostat may increase your risk of developing bone marrow disorders or other cancers. Tell your doctor if you feel unusually tired or have a fever, pale skin, easy bruising, or bone pain.
Before taking this medicine
Using tazemetostat may increase your risk of developing bone marrow disorders or other cancers, such as leukemia or lymphoma. Ask your doctor about this risk.
You may need to have a negative pregnancy test before starting this treatment.
Tazemetostat can harm an unborn baby or cause birth defects if the mother or the father is using tazemetostat.
If you are a woman, do not use tazemetostat if you are pregnant. Use effective nonhormonal birth control to prevent pregnancy while you are using this medicine and for at least 6 months after your last dose.
If you are a man, use effective birth control if your sex partner is able to get pregnant. Keep using birth control for at least 6 months after your last dose.
Tazemetostat can make hormonal birth control less effective, including birth control pills, injections, implants, skin patches, and vaginal rings. To prevent pregnancy while using tazemetostat, use a barrier form of birth control: condom, diaphragm, cervical cap, or contraceptive sponge.
Do not breastfeed while using this medicine, and for at least 1 week after your last dose.
How should I take tazemetostat?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
You may take tazemetostat with or without food.
Swallow the tablet whole and do not crush, chew, or break it.
If you vomit shortly after taking tazemetostat, do not take another dose. Wait until ...
