Tazverik
Generic name:tazemetostat [ TAZ-e-MET-oh-stat ]
Drug class:Miscellaneous antineoplastics
What is Tazverik?
Tazverik is used to treat adults and pediatric patients aged 16 years and older with advanced epithelioid sarcoma, a rare slow-growing type of soft tissue cancer. This medicine is used when the cancer has spread to other parts of the body (metastatic) or cannot be removed with surgery.
Tazverik is also used to treat follicular lymphoma when the disease has come back or did not respond to treatment in adults:
- whose tumors have an abnormal EZH2 gene, and who have been treated with at least two prior medicines. Your healthcare provider will perform a test to make sure Tazverik is right for you.
- who have no other satisfactory treatment options.
Tazverik was approved by the US Food and Drug Administration (FDA) on an "accelerated" basis. In clinical studies, some people responded to this medicine, but further studies are needed.
Warnings
Using Tazverik may increase your risk of developing bone marrow disorders or other cancers.
Tazverik can cause serious side effects, including:
- Risk of new cancers. An increase in new (second) cancers has happened in people who were treated with Tazverik. Talk with your healthcare provider about your risk of developing new cancers. Tell your healthcare provider if you are more tired than usual, or have easy bruising, fever, bone pain, or paleness.
Before taking this medicine
Using Tazverik may increase your risk of developing bone marrow disorders or other cancers, such as leukemia or lymphoma. Ask your doctor about this risk.
You may need to have a negative pregnancy test before starting this treatment.
Tazemetostat can harm an unborn baby or cause birth defects if the mother or the father is using this medicine.
If you are a woman, do not use Tazverik if you are pregnant. Use effective nonhormonal birth control to prevent pregnancy while you are using this medicine and for at least 6 months after your last dose.
If you are a man, use effective birth control if your sex partner is able to get pregnant. Keep using birth control for at least 6 months after your last dose.
Tazemetostat can make hormonal birth control less effective, including birth control pills, injections, implants, skin patches, and vaginal rings. To prevent pregnancy while using this medicine, use a barrier form of birth control: condom, diaphragm, cervical cap, or contraceptive sponge.
Do not breastfeed while using this medicine, and for at least 1 week after your last dose.
How should I take Tazverik?
Take Tazverik exactly as prescribed by ...
