Tenecteplase
Generic name: tenecteplase [ ten-EK-te-plase ]
Brand name: TNKase
Dosage forms: intravenous kit (50 mg); intravenous powder for injection (50 mg)
Drug class:Thrombolytics
What is tenecteplase?
Tenecteplase is a thrombolytic (THROM-bo-LIT-ik) drug, sometimes called a "clot-busting" drug. It helps your body produce a substance that dissolves unwanted blood clots.
Tenecteplase is used to prevent death in people who have had a heart attack (acute myocardial infarction).
Tenecteplase may also be used for purposes not listed in this medication guide.
Warnings
If possible before you receive tenecteplase, tell your doctor if you have a brain tumor or aneurysm, high blood pressure, hemophilia or other bleeding disorder, a history of stroke, or if you have recently had a head injury or surgery on your brain or spinal cord.
In an emergency, you may not be able to tell caregivers about your health conditions. Make sure any doctor caring for you afterward knows you received tenecteplase.
Before taking this medicine
You should not be treated with tenecteplase if you are allergic to it, or if you have:
active bleeding inside your body;
a recent history of medical trauma or injury;
severe or uncontrolled high blood pressure;
a genetic disorder affecting the blood vessels in your brain;
a brain tumor, blood vessel disorder, or aneurysm (dilated blood vessel);
a bleeding or blood clotting disorder (such as hemophilia);
a history of stroke; or
if you have had brain or spinal cord injury or surgery within the past 2 months.
If possible before you receive tenecteplase, tell your doctor if you have ever had:
a stroke;
bleeding in your brain, stomach, intestines, or urinary tract;
high blood pressure;
heart problems;
an infection of the lining of your heart (also called bacterial endocarditis);
liver or kidney disease;
eye problems caused by diabetes;
severe bruising or infection around a vein where an IV was placed;
a serious injury or major surgery;
an organ biopsy; or
if you are pregnant or have recently had a baby.
In an emergency, you may not be able to tell caregivers if you are pregnant or breast feeding. Make sure any doctor caring for your pregnancy or your baby knows you received this medicine.
How is tenecteplase given?
Tenecte...
