Tepmetko

Generic name:tepotinib
Dosage form: tablets, for oral use
Drug class:Multikinase inhibitors

Medically reviewed by Judith Stewart, BPharm. Last updated on Aug 31, 2021.

Warnings

 Tepmetko may cause serious side effects, including:

• Lung problems. Tepmetko may cause severe or life-threatening swelling (inflammation) of the lungs during treatment that can lead to death. Tell your healthcare provider right away if you develop any new or worsening symptoms of lung problems, including:
  • trouble breathing
  • shortness of breath
  • cough
  • fever

See Tepmetko side effects for more information about side effects.

What is Tepmetko?

Tepmetko is a prescription medicine used to treat adults with non-small cell lung cancer (NSCLC) that:

• has spread to other parts of the body (metastatic), and
• whose tumors have an abnormal mesenchymal epithelial transition (MET) gene. Your healthcare provider will perform a test to make sure that Tepmetko is right for you.

It is not known if this medicine is safe and effective in children.

Before you receive Tepmetko

Tell your healthcare provider about all of your medical conditions, including if you:

• have or have had lung or breathing problems other than your lung cancer
• have or have had liver problems
• are pregnant or plan to become pregnant. Tepmetko can harm your unborn baby.
  Females who are able to become pregnant:
  • Your healthcare provider may do a pregnancy test before you start treatment.
  • You should use effective birth control (contraception) during treatment and for 1 week after the final dose. Talk to your healthcare provider about birth control methods that may be right for you.

Males with female partners who are able to become pregnant should use effective birth control during treatment, and for 1 week after the final dose.