Tepotinib
Generic name: tepotinib [ tep-OH-ti-nib ]
Brand name: Tepmetko
Dosage form: oral tablet (225 mg)
Drug class:Multikinase inhibitors
What is tepotinib?
Tepotinib is used to treat a certain type of non-small cell lung cancer that has a specific genetic marker (an abnormal "MET" gene). Your doctor will test you for this gene.
Tepotinib was approved by the US Food and Drug Administration (FDA) on an "accelerated" basis. In clinical studies, some people responded to tepotinib, but further studies are needed.
Tepotinib may also be used for purposes not listed in this medication guide.
Warnings
Tepotinib can cause severe or life-threatening side effects on your lungs. Call your doctor at once if you have a cough, fever, or trouble breathing.
Before taking this medicine
Tell your doctor if you have ever had:
breathing problems before you had lung cancer; or
You may need to have a negative pregnancy test before starting this treatment.
Both men and women using tepotinib should use effective birth control to prevent pregnancy. Tepotinib can harm an unborn baby if the mother or father is using this medicine.
Keep using birth control for at least 1 week after your last dose. Tell your doctor right away if a pregnancy occurs while either the mother or the father is using tepotinib.
Do not breastfeed while using this medicine, and for at least 1 week after your last dose.
How should I take tepotinib?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Take with food at the same time each day.
Swallow the tablet whole and do not crush, chew, or break it.
If you vomit shortly after taking tepotinib, do not take another dose. Wait until your next scheduled dose time to take the medicine again.
Do not change your dose or stop using this medicine without your doctor's advice.
Store the tablets in the foil blister pack at room temperature, away from moisture and heat.
What happens if I miss a dose?
Use the medicine as soon as you can, but skip the missed dose if your next dose is due in less than 8 hours. Do not use two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking tepotinib?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
