Teprotumumab
Generic name: teprotumumab [ TEP-roe-TOOM-ue-mab ]
Brand name: Tepezza
Dosage form: intravenous powder for injection (trbw 500 mg)
Drug class:Growth hormone receptor blockers
What is teprotumumab?
Teprotumumab is used to treat thyroid eye disease (sometimes called Graves Eye Disease).
Thyroid eye disease is an autoimmune disorder in which the immune system attacks tissues around the eyes. Symptoms include dry or watery eyes, eye redness, bulging eyes, vision problems, and difficulty closing the eyes.
Teprotumumab may also be used for purposes not listed in this medication guide.
Warnings
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
Before taking this medicine
Tell your doctor if you have ever had:
diabetes or hyperglycemia (high blood sugar);
Teprotumumab may harm an unborn baby. Use effective birth control to prevent pregnancy while you are receiving teprotumumab and for at least 6 months after your last dose. Tell your doctor if you become pregnant.
It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.
How is teprotumumab given?
Teprotumumab is given as an infusion into a vein. A healthcare provider will give you this injection.
Teprotumumab is usually given once every 3 weeks for a total of 8 doses.
This medicine must be given slowly, and the infusion can take 60 to 90 minutes to complete.
What happens if I miss a dose?
Call your doctor for instructions if you miss an appointment for your teprotumumab injection.
What happens if I overdose?
Since teprotumumab is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.
What should I avoid while receiving teprotumumab?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
Teprotumumab side effects
Get emergency medical help if you have signs of an allergic reaction:hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Some side effects may occur during an injection or within 1.5 hours afterward. Tell your car...
