Teriflunomide

Generic name: teriflunomide [ ter-i-FLOO-noe-mide ]
Brand name: Aubagio
Dosage form: oral tablet (14 mg; 7 mg)
Drug class:Selective immunosuppressants

Medically reviewed by Drugs.com on Dec 1, 2020. Written by Cerner Multum.

What is teriflunomide?

Teriflunomide is used to treat relapsing forms of multiple sclerosis in adults (including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease).

Teriflunomide may also be used for purposes not listed in this medication guide.

Warnings

Do not use teriflunomide if you are pregnant or may become pregnant. You will need to have a negative pregnancy test before starting this treatment.

Teriflunomide can cause serious liver problems that may result in the need for a liver transplant. Your liver function will need to be tested before and during treatment with teriflunomide. Tell your doctor if you have a history of liver disease.

Call your doctor at once if you have signs of liver problems: upper stomach pain, loss of appetite, dark urine, or jaundice (yellowing of the skin or eyes).

Before taking this medicine

You should not use teriflunomide if you are allergic to teriflunomide or leflunomide, or if:

• you have severe liver disease; or

• you are also taking leflunomide (Arava).

Do not use teriflunomide if you are pregnant or may become pregnant You will need to have a negative pregnancy test before starting this treatment. Avoid getting pregnant until after you stop taking teriflunomide and undergo a "drug elimination" procedure to help rid your body of this medicine. Stop taking teriflunomide and call your doctor right away if you miss a period or think you might be pregnant.

Tell your doctor if you have ever had:

• liver or kidney disease;

• a fever, or uncontrolled infections;

• numbness or tingling that is unlike your usual MS symptoms;

• serious skin problems when taking medicines;

• diabetes;

• high blood pressure;

• tuberculosis; or

• breathing problems.

Use birth control to prevent pregnancy while you are taking this medicine. After you stop taking teriflunomide, continue using birth control until you have received blood tests to make sure the drug h...