Tetracaine and oxymetazoline (Nasal)

Medically reviewed by Drugs.com. Last updated on Jan 26, 2022.

Commonly used brand name(s)

In the U.S.

• Kovanaze

Chemical Class: Tetracaine

Uses for tetracaine and oxymetazoline

Tetracaine and oxymetazoline combination nasal spray is used to numb the affected tooth (Teeth 4-13 and A-J) before a dental procedure in adults and children weighing 40 kilograms (kg) or more.

Tetracaine and oxymetazoline is to be given by or under the direct supervision of your dentist or other health care professional.

Before using tetracaine and oxymetazoline

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For tetracaine and oxymetazoline, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to tetracaine and oxymetazoline or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of tetracaine and oxymetazoline combination nasal spray in children younger than 3 years of age and in children weighing less than 40 kg. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of tetracaine and oxymetazoline combination nasal spray in the elderly. However, elderly patients are more likely to have increased blood pressure and kidney, liver, or heart problems, which may require caution in patients receiving tetracaine and oxymetazoline.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving tetracaine and oxymetazoline, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using tetracaine and oxymetazoline with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Amineptine
• Amitriptyline
• Amitriptylinoxide
• Amoxapine
• Bupivacaine
• Carteolol
• Carvedilol
• Clomipramine
• Desipramine
• Dibenzepin
• Doxepin
• Fentanyl Citrate
• Furazolidone
• Hyaluronidase
• Imipramine
• Iproniazid
• Isocarboxazid
• Labetalol
• Levobunolol
• Linezolid
• Lofepramine
• Melitr...