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Tezepelumab
  • Treatments
  • Asthma

Tezepelumab

Generic name: tezepelumab [ TEZ-e-PEL-ue-mab ]
Brand name: Tezspire
Dosage form: subcutaneous solution (210 mg/1.91 mL)
Drug class:Selective immunosuppressants

Medically reviewed by Drugs.com on Mar 30, 2022. Written by Cerner Multum.

What is tezepelumab?

Tezepelumab is used together with other medicines for the maintenance treatment of severe asthma in people 12 years and older and whose asthma is not controlled with their current medication.

Tezepelumab is not a fast-acting rescue medicine for asthma attacks or bronchospasms. Seek medical attention if your breathing problems get worse quickly, or if you think your medications are not working.

Tezepelumab may also be used for purposes not listed in this medication guide.

Warnings

Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.

Before taking this medicine

You should not be treated with tezepelumab if you are allergic to it.

Tell your doctor if you have ever had:

  • a severe allergic reaction;

  • a parasite (helminth) infection; or

  • if you are scheduled to receive or have received a live vaccine recently.

Tell your doctor if you are pregnant, plan to get pregnant, or if you are breastfeeding or plan to breastfeed.

How should I receive tezepelumab?

Tezepelumab is injected under the skin, usually once every 4 weeks. A healthcare provider will give you this injection.

You will be watched closely for a short time after each injection, to make sure you do not have an allergic reaction.

If you also use a steroid medication, you should not stop using it suddenly. Follow your doctor's instructions about tapering your dose.

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your tezepelumab injection.

What happens if I overdose?

Since tezepelumab is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

What should I avoid while receiving tezepelumab?

Avoid receiving a "live" vaccine. Live vaccines include measles, mumps, rubella (MMR), rotavirus, typhoid, yellow fever, varicella (chickenpox), and zoster (shingles).

Tezepelumab side effects

Get emergency medical help if you have signs of an allergic reaction:hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Some side effects may occur during or after the injection. Tell your caregiver if you feel dizzy, nauseated, light-headed, itchy, sho...