Thallous Chloride

Generic name: Thallous Chloride tl-201
Dosage form: injection, solution
Drug class:Diagnostic radiopharmaceuticals

Medically reviewed by Drugs.com. Last updated on Nov 22, 2021.

Indications and Usage for Thallous Chloride

Thallous Chloride Tl 201 Injection is a diagnostic radiopharmaceutical indicated for

• Myocardial perfusion imaging with planar scintigraphy or single-photon emission computed tomography (SPECT) for the diagnosis of coronary artery disease by localization of:
  • Non-reversible defects (myocardial infarction) which may have prognostic value regarding survival.
  • Reversible defects (myocardial ischemia) when used in conjunction with exercise or pharmacologic stress.
• Localization of sites of parathyroid hyperactivity pre- and post-operatively in patients with elevated serum calcium and parathyroid hormone levels.

Thallous Chloride Dosage and Administration

Radiation Safety

Thallous Chloride Tl 201 Injection emits radiation and must be handled with appropriate safety measures and in accordance with the “as low as reasonably achievable” (ALARA) principle of radioactivity dosing.

Use the lowest dose of Thallous Chloride Tl 201 Injection necessary to obtain the intended diagnostic image. Individualize the dose and consider factors such as body size, and the equipment and technique to be employed.

Recommended Dose

Myocardial perfusion

• Planar scintigraphy: 37 to 74 MBq (1 to 2 mCi) administered intravenously
• SPECT: 74 to 111 MBq (2 to 3 mCi) administered intravenously

Parathyroid hyperactivity localization

Planar or SPECT: 75 to 130 MBq (2 to 3.5 mCi) administered intravenously

Drug Administration and Imaging

For resting myocardial stud..