Ticarcillin and clavulanate (Intravenous)

Medically reviewed by Drugs.com. Last updated on Apr 8, 2022.

Commonly used brand name(s)

In the U.S.

• Timentin
• Timentin Novaplus

Pharmacologic Class: Ticarcillin

Uses for ticarcillin and clavulanate

Ticarcillin and clavulanate combination is used to treat bacterial infections in many different parts of the body.

Ticarcillin and clavulanate combination is an antibiotic that belongs to the group of medicines known as penicillins and beta-lactamase inhibitors. It works by killing the bacteria or preventing their growth. However, ticarcillin and clavulanate will not work for colds, flu, or other virus infections.

Ticarcillin and clavulanate was to be given only by or under the direct supervision of a doctor.

The ticarcillin/clavulanate combination was withdrawn from the United States market on February 9, 2015.

Before using ticarcillin and clavulanate

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For ticarcillin and clavulanate, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to ticarcillin and clavulanate or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of ticarcillin and clavulanate combination in children. However, safety and efficacy have not been established in infants younger than 3 months of age.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of ticarcillin and clavulanate combination in the elderly. However, elderly patients are more likely to have age-related kidney or heart problems, which may require an adjustment in the dose for patients receiving ticarcillin and clavulanate combination.

Breastfeeding

Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving ticarcillin and clavulanate, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using ticarcillin and clavulanate with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Amifampridine
• Bupropion
• Desogestrel
• Dienogest
• Donepezil
• Drospirenone
• Estradiol
• Ethinyl Estradiol
• Ethynodiol
• Gestodene
• Levonorgestr...