Medically reviewed by Drugs.com. Last updated on Feb 26, 2022.
An increase in all-cause mortality was observed in a meta-analysis of Phase 3 and 4 clinical trials in tigecycline-treated patients versus comparator. The cause of this mortality risk difference of 0.6% (95% CI, 0.1 to 1.2) has not been established. Tigecycline should be reserved for use in situations when alternative treatments are not suitable .
Commonly used brand name(s)
In the U.S.
- Tygacil
Available Dosage Forms:
- Powder for Solution
Therapeutic Class: Antibiotic
Chemical Class: Glycylcycline
Uses for tigecycline
Tigecycline injection is used to treat bacterial infections in many different parts of the body (eg, infections on the skin, stomach, or lungs). It works by killing bacteria or preventing their growth. However, tigecycline will not work for colds, flu, or other virus infections. This is a tetracycline antibiotic.
Tigecycline is to be given only by or under the direct supervision of your doctor.
Before using tigecycline
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For tigecycline, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to tigecycline or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Use of tigecycline injection in children is not recommended. Safety and efficacy have not been established.
Tigecycline may cause permanent discoloration of the teeth and slow down the growth of bones. Tigecycline should not be given to children 8 years of age and younger, unless directed by the child's doctor.
Geriatric
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of tigecycline injection in the elderly.
Breastfeeding
There are no adeq..
