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Tiopronin
  • Treatments
  • Cystinuria

Tiopronin

Generic name: tiopronin [ tye-OH-proe-nin ]
Brand names: Thiola, Thiola EC
Dosage forms: oral delayed release tablet (100 mg; 300 mg); oral tablet (100 mg)
Drug class:Miscellaneous genitourinary tract agents

Medically reviewed by Drugs.com on Feb 28, 2022. Written by Cerner Multum.

What is tiopronin?

Tiopronin is used together with diet, fluids, and other medicines to help prevent kidney stones in adults and children weighing at least 44 pounds (20 kilograms).

Tiopronin is usually given after diet, increased fluid intake, or other medications have failed.

Tiopronin may also be used for purposes not listed in this medication guide.

Warnings

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Before taking this medicine

You should not use tiopronin if you are allergic to it.

tiopronin should not be given to a child who is unable to swallow a tablet.

Tell your doctor if you are pregnant. It is not known whether tiopronin will harm an unborn baby. However, having a kidney stone during pregnancy may cause complications such as low birth weight or premature birth. The benefit of preventing kidney stones may outweigh any risks to the baby.

You should not breastfeed while using tiopronin.

How should I take tiopronin?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Take the medicine at the same time each day, with or without food.

Swallow the tablet whole and do not crush, chew, or break it.

Drink plenty of liquids while you are taking tiopronin.

You will need frequent urine tests.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking tiopronin?

Avoid drinking alcohol 2 hours before and 3 hours after taking tiopronin.

Tiopronin side effects

Get emergency medical help if you have signs of an allergic reaction:hives, rash; fever, swollen glands, joint pain; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have signs of kidney problems--puffy eyes, swelling in your ankles or feet, weight gain, or u...