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Tirofiban
  • Treatments
  • Acute Coronary Syndrome

Tirofiban

Generic name: tirofiban [ tye-roe-FYE-ban ]
Brand name: Aggrastat
Dosage form: intravenous solution (250 mcg/mL; 50 mcg/mL)
Drug class:Glycoprotein platelet inhibitors

Medically reviewed by Drugs.com on Feb 8, 2022. Written by Cerner Multum.

What is tirofiban?

Tirofiban is used to prevent blood clots or heart attack in people with severe chest pain or other conditions, and in those who are undergoing a procedure called angioplasty (to open blocked arteries).

Tirofiban may also be used for purposes not listed in this medication guide.

Warnings

You should not receive tirofiban if you have any active internal bleeding (stomach, intestines, etc), a history of bleeding or blood-clotting disorder, if you have ever had low blood platelets after being treated with tirofiban, or if you have had any type of surgery, injury, or medical emergency within the past 30 days.

Before taking this medicine

You should not be treated with tirofiban if you are allergic to it, or if you have:

  • any active internal bleeding (stomach, intestines, etc);

  • a history of bleeding or blood-clotting disorder;

  • if you have ever had low blood platelets after being treated with tirofiban; or

  • if you have had any type of surgery, injury, or medical emergency within the past 30 days.

Tell your doctor if you have ever had:

  • kidney disease.

Tell your doctor if you are pregnant or plan to become pregnant during treatment, especially if you are also taking aspirin.

You should not breast-feed while using this medicine.

How is tirofiban given?

Tirofiban is given as an infusion into a vein. A healthcare provider will give you this injection.

While using tirofiban, you may need frequent blood tests.

What happens if I miss a dose?

Because you will receive tirofiban in a clinical setting, you are not likely to miss a dose.

What happens if I overdose?

Since this medication is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

What should I avoid while receiving tirofiban?

Ask your doctor before taking a nonsteroidal anti-inflammatory drug (NSAID) such as aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib (Celebrex), diclofenac,

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