Tisotumab vedotin
Generic name: tisotumab vedotin [ tye-SOT-ue-mab-ve-DOE-tin ]
Brand name: Tivdak
Dosage form: intravenous powder for injection (tftv 40 mg)
Drug class:Miscellaneous antineoplastics
What is tisotumab vedotin?
Tisotumab vedotin is used to treat cervical cancer that has spread to other parts of the body (metastatic) after other treatments did not work or stopped working.
Tisotumab vedotin may also be used for purposes not listed in this medication guide.
Warnings
Using tisotumab vedotin can cause changes to the surface of your eye and in some cases may cause serious eye problems including vision loss. Tell your doctor if you have eye redness, dryness, or irritation, or if you notice vision changes or white patches on your eyes.
An eye doctor will need to check your eyes before and during treatment with tisotumab vedotin. You will also need to use prescription eye medications each time you receive a tisotumab vedotin infusion. Be sure to bring all eye medications with you to each infusion appointment.
Before taking this medicine
Tell your doctor if you have ever had:
vision or eye problems;
bleeding problems;
liver disease; or
numbness or tingling (neuropathy) in your hands and feet.
Tisotumab vedotin can harm an unborn baby if the mother or the father is using tisotumab vedotin.
If you are a woman, you may need a pregnancy test to make sure you are not pregnant. Use birth control while using this medicine and for at least 2 months after your last dose.
If you are a man, use birth control if your sex partner is able to get pregnant. Keep using birth control for at least 4 months after your last dose.
Tell your doctor right away if a pregnancy occurs.
This medicine may affect fertility (ability to have children) in men. However, it is important to use birth control to prevent pregnancy because tisotumab vedotin can harm an unborn baby.
Do not breastfeed while using this medicine, and for at least 3 weeks after your last dose.
How is tisotumab vedotin given?
Tisotumab vedotin is injected into a vein by a healthcare provider.
This medicine must be given slowly over 30 minutes.
Tisotumab vedotin is usually given once every 3 weeks until your body no longer responds to the medication or you have certain side effects.
Using tisotumab vedotin can cause changes to the surface of your eye and in some cases may cause serious eye problems including vision loss. An eye doctor will need to check your eyes bef...
