Tisseel
Generic name:fibrin sealant topical [ FYE-brin-SEE-lant-TOP-i-kal ]
Brand names: Artiss, Artiss Duo Set, Artiss Duploject, Tisseel, Tisseel Duploject Kit, Tisseel Valupak Kit
Drug class:Miscellaneous coagulation modifiers
The Tisseel brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.
What is Tisseel?
Fibrin sealant is made of two substances from human plasma that work together to help your blood clot.
Tisseel is used to help control bleeding during surgery when other ways to close a wound or incision (such as stitches, bands, or heat) cannot be used. This medicine may also be used to prevent leaks from a wound left in stomach tissue after a colostomy is removed.
Tisseel is sometimes used to help skin tissues stick together during skin graft procedures or cosmetic surgery.
Tisseel may also be used for purposes not listed in this medication guide.
Warnings
You should not be treated with Tisseel if you are allergic to cows or products made from cows.
Before taking this medicine
You should not be treated with Tisseel if you are allergic to cows or products made from cows.
It is not known whether Tisseel will harm an unborn baby. Tell your doctor if you are pregnant.
It is not known whether fibrin sealant topical passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
How should I use Tisseel?
Tisseel can be sprayed or dripped onto the affected skin or surgical area. Tisseel is applied by a healthcare professional in a surgical or clinical setting.
Tisseel is made from human plasma (part of the blood) which may contain viruses and other infectious agents. Donated plasma is tested and treated to reduce the risk of it containing infectious agents, but there is still a small possibility it could transmit disease. Talk with your doctor about the risks and benefits of using this medication.
Some people develop symptoms of a viral infection after being treated with Tisseel. Call your doctor if you have flu-like symptoms such as fever, chills, drowsiness, or a runny nose. You may also have joint pain and a skin rash about 2 weeks after the start of your flu symptoms.