Tivozanib
Generic name: tivozanib [ tye-VOE-zan-ib ]
Brand name: Fotivda
Dosage form: oral capsule (1340 mcg; 890 mcg)
Drug class:VEGF/VEGFR inhibitors
What is tivozanib?
Tivozanib is used to treat advanced kidney cancer in adults, after at least two other cancer treatments did not work or have stopped working.
Tivozanib may also be used for purposes not listed in this medication guide.
Warnings
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
Before taking this medicine
Tell your doctor if you have ever had:
heart problems;
a blood clot, heart attack, or stroke;
bleeding problems;
surgery, including oral surgery;
a wound that has not healed;
a thyroid disorder;
liver disease; or
an allergy to aspirin or yellow dye (tartrazine).
You may need to have a negative pregnancy test before starting this treatment.
Both men and women using tivozanib should use effective birth control to prevent pregnancy. Tivozanib can harm an unborn baby if the mother or father is using this medicine.
Keep using birth control for at least 1 month after your last dose. Tell your doctor right away if a pregnancy occurs while either the mother or the father is using tivozanib.
Pregnancy may be less likely to occur while the mother or the father is using this medicine. Both men and women should still use birth control to prevent pregnancy because the medicine can harm an unborn baby.
Do not breastfeed while using this medicine, and for at least 1 month after your last dose.
How should I take tivozanib?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Tivozanib is given in a 28-day treatment cycle. You may need to use the medicine only during the first 21 days of each cycle. Your doctor will determine how long to treat you with this medicine.
You may take tivozanib with or without food.
Swallow the capsule whole and do not crush, chew, break, or open it.
Your blood pressure will need to be checked often. You may also need blood or urine tests.
You may be given other medication to help prevent nausea
