Tolak

Generic name:fluorouracil topical [ FLOOR-oh-URE-a-sil-TOP-i-kal ]
Brand names: Carac, Efudex, Fluoroplex, Tolak
Drug class:Topical antineoplastics

Medically reviewed by Drugs.com on Dec 4, 2020. Written by Cerner Multum.

What is Tolak?

Tolak (for the skin) is used to treat scaly overgrowths of skin (actinic or solar keratosis).

Tolak is also used to treat superficial basal cell carcinoma.

Tolak may also be used for purposes not listed in this medication guide.

Warnings

Do not use if you are pregnant. Use effective birth control, and tell your doctor if you become pregnant during treatment.

Before taking this medicine

You should not use Tolak if you are allergic to fluorouracil, or if you have:

• a metabolic disorder called DPD (dihydropyrimidine dehydrogenase) deficiency.

Do not use Tolak if you are pregnant. It could harm the unborn baby or cause birth defects. Use effective birth control to prevent pregnancy while you are using this medicine.

You should not breastfeed while using Tolak.

Tolak is not approved for use by anyone younger than 18 years old.

How should I use Tolak?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Do not take by mouth. Topical medicine is for use only on the skin.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

Wash your hands before and immediately after applying this medicine, unless it is being used to treat a hand condition. Caregivers who apply this medicine should wear rubber gloves.

Apply only enough medicine to cover the affected skin with a thin film.

Do not apply Tolak to skin that is irritated, peeling, or infected or on open wounds. Wait until these conditions have fully healed before using this medicine.

Do not cover the treated skin area with bandaging or plastic unless your doctor tells you to.

You may need to use Tolak for up to 6 weeks. Treated skin may have an undesirable appearance as it heals, which may take several weeks.

Store at room temperature away from moisture and heat. Do not freeze. Keep the medicine container tightly closed when not in use.

Do not use Tolak to treat a skin condition that has not been checked by your doctor.