Tolak Cream

Generic name:fluorouracil
Dosage form: cream
Drug class:Topical antineoplastics

Medically reviewed by Drugs.com. Last updated on Feb 21, 2022.

Indications and Usage for Tolak Cream

Tolak (fluorouracil) Cream is indicated for the topical treatment of actinic keratosis lesions of the face, ears, and/or scalp.

Tolak Cream Dosage and Administration

Prior to application of Tolak Cream, wash, rinse, and dry the treatment areas. Apply Tolak Cream once daily in an amount sufficient to cover the lesions of the face, ears, and/or scalp with a thin film, using the fingertips to gently massage the medication uniformly into the skin. Apply Tolak Cream for a period of 4 weeks as tolerated. Thoroughly wash hands following Tolak Cream application.

Tolak Cream is for topical use only. Do not apply to eyes, nose, mouth or mucous membranes. Not for ophthalmic, oral or intravaginal use.

Dosage Forms and Strengths

Cream: 40 mg of fluorouracil per gram (4%) of white cream in 40 gram tubes.

Contraindications

Tolak Cream is contraindicated:

• During pregnancy [see Warnings and Precautions (5.5, 8.1)]
• In patients with dihydropyrimidine dehydrogenase (DPD) deficiency [see Warnings and Precautions (5.6)]

Pregnancy

Tolak Cream may cause fetal harm when administered during pregnancy and is contraindicated in women who are pregnant. If this drug is used during pregnancy, or if the patient becomes pregnant while using this drug, the patient should be apprised of the potential hazard to the fetus.

Dihydropyrimidine Dehydrogenase Deficiency

Tolak Cream is contraindicated in patients with dihydropyrimidine dehydrogenase (DPD) deficiency.

Warnings and Precautions

Application Site Adverse Reactions

Application s...