Tranylcypromine
Generic name: tranylcypromine [ TRAN-il-SIP-roe-meen ]
Brand name: Parnate
Dosage form: oral tablet (10 mg)
Drug class:Monoamine oxidase inhibitors
What is tranylcypromine?
Tranylcypromine is a monoamine oxidase inhibitor (MAOI) that works by increasing the levels of certain chemicals in the brain.
Tranylcypromine is used to treat major depressive episodes in adults when other medicines have not been effective.
Tranylcypromine may also be used for purposes not listed in this medication guide.
Warnings
Some young people have thoughts about suicide when first taking an antidepressant. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor.
There are many other drugs, foods, and beverages that can cause serious medical problems if you take them together with tranylcypromine. Tell your doctor about all your current medicines and any you start or stop using. Avoid drinking alcohol, and learn about the foods you should avoid.
Eating foods that contain a lot of tyramine while taking tranylcypromine can cause dangerously high blood pressure. Symptoms include a sudden and severe headache, nausea, vomiting, fever, cold sweat, dilated pupils, light sensitivity, fast or pounding heartbeats, neck stiffness, weakness, or problems with vision or speech.
Before taking this medicine
You should not use tranylcypromine if you are allergic to it, or if you have:
pheochromocytoma (tumor of the adrenal gland).
A dangerous drug interaction could occur between tranylcypromine and certain other medications you used in the past 14 days. You should not take tranylcypromine if you also use:
other antidepressants;
buspirone, carbamazepine, reserpine, tapentadol, tetrabenazine, tryptophan, SAM-e;
diet pills, stimulants, ADHD medications, cough and cold or allergy medicines;
another MAO inhibitor--isocarboxazid, linezolid, methylene blue i...
