Tretin-X Cream
Generic name:tretinoin
Dosage form: cream
Drug class:Topical acne agents
Medically reviewed by Drugs.com. Last updated on Jul 22, 2021.
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The Tretin-X brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.
Tretin-X Cream Description
TRETIN•X Cream, USP is used for the topical treatment of acne vulgaris. Each gram of TRETIN•X cream contains tretinoin in either of five strengths, 0.1% (1 mg), 0.075% (0.75 mg) 0.05% (0.5 mg), 0.0375% (0.375 mg) or 0.025% (0.25 mg) in a hydrophilic cream vehicle of stearic acid, isopropyl myristate, polyoxyl 40 stearate, stearyl alcohol, xanthan gum, sorbic acid, butylated hydroxytoluene, and purified water. Chemically, tretinoin is all-trans-retinoic acid. It has a molecular weight of 300.44 and has the following structural formula:
C20H28O2
Tretin-X Cream - Clinical Pharmacology
Although the exact mode of action of TRETIN•X is unknown, current evidence suggests that topical tretinoin decreases cohesiveness of follicular epithelial cells with decreased microcomedo formation. Additionally, tretinoin stimulates mitotic activity and increased turnover of follicular epithelial cells causing extrusion of the comedones.
Indications and Usage for Tretin-X Cream
TRETIN•X cream is indicated for topical application in the treatment of acne vulgaris. The safety and efficacy of the long-term use of this product in the treatment of other disorders have not been established.
Contraindications
Use of the product should be discontinued if hypersensitivity to any of the ingredients is noted.
Warnings
Keep out of reach of children. Keep tube tigh...
