Trexall
Generic name:methotrexate (oral) [ meth-oh-TREX-ate ]
Brand names: Trexall, Xatmep
Drug classes:Antimetabolites, Antipsoriatics, Antirheumatics, Other immunosuppressants
What is Trexall?
Trexall is used to treat leukemia and certain types of cancer of the breast, skin, head and neck, lung, or uterus.
Trexall is also used to treat severe psoriasis and rheumatoid arthritis in adults.
Trexall is also used to treat active polyarticular-course juvenile rheumatoid arthritis in children.
Trexall is sometimes given when other medicines have not been effective.
Trexall may also be used for purposes not listed in this medication guide.
Warnings
Trexall may cause injury or death to an unborn baby and should not be used during pregnancy to treat arthritis or psoriasis. This medicine is sometimes used to treat cancer during pregnancy. Tell your doctor if you are pregnant or plan to become pregnant.
Do not use Trexall to treat psoriasis or rheumatoid arthritis if you have low blood cell counts, a weak immune system, alcoholism or chronic liver disease, or if you are breastfeeding.
YOU MAY NOT NEED TO TAKE Trexall EVERY DAY. Some people have died after incorrectly taking this medicine every day. You must use the correct dose for your condition.
Trexall can cause serious or fatal side effects. Tell your doctor if you have diarrhea, mouth sores, cough, shortness of breath, upper stomach pain, dark urine, numbness or tingling, muscle weakness, confusion, seizure, or skin rash that spreads and causes blistering and peeling.
Before taking this medicine
You should not use Trexall if you are allergic to it. You may not be able to take this medicine if you have:
alcoholism, cirrhosis, or chronic liver disease;
low blood cell counts;
a weak immune system or bone marrow disorder; or
if you are pregnant or breastfeeding.
Trexall is sometimes used to treat cancer in people who have a condition listed above. Your doctor will decide if this treatment is right for you.
Tell your doctor if you have ever had:
liver problems, especia...
