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Tri-Luma
  • Treatments
  • Melasma

Tri-Luma

Generic name:fluocinolone, hydroquinone, and tretinoin topicalFLOO-oh-SIN-oh-lone, HYE-droe-KWIN-one, TRET-in-oin ]
Drug class:Topical depigmenting agents

Medically reviewed by Drugs.com on Feb 25, 2022. Written by Cerner Multum.

What is Tri-Luma?

Fluocinolone is a steroid that reduces inflammation or swelling.

Hydroquinone is a skin bleaching agent.

Tretinoin is a form of vitamin A that helps the skin to renew itself more quickly.

Tri-Luma (for use on the skin) is a combination medicine used to treat melasma (dark skin patches) on the face.

Tri-Luma may also be used for purposes not listed in this medication guide.

Warnings

Avoid exposure to sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

Before taking this medicine

You should not use Tri-Luma if you are allergic to fluocinolone, hydroquinone, or tretinoin.

To make sure this medicine is safe for you, tell your doctor if you have:

Using Tri-Luma during pregnancy could harm the unborn baby. Tell your doctor if you are pregnant or if you become pregnant while using this medicine.

The pill form of tretinoin is known to cause birth defects. Although your skin does not absorb as much tretinoin as if you were taking the medicine by mouth, it may be best not to use Tri-Luma if you are pregnant. Talk to your doctor first.

Hormonal contraception (birth control pills, injections, implants, skin patches, and vaginal rings) can cause melasma to get worse. Ask your doctor about using a non hormonal birth control (condom, diaphragm with spermicide) instead.

It is not known whether fluocinolone, hydroquinone, and tretinoin topical passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

This medicine is not approved for use by anyone younger than 18 years old.

How should I use Tri-Luma?

Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Do not take by mouth. Tri-Luma is for use only...