Trimethobenzamide (Oral)

Medically reviewed by Drugs.com. Last updated on Feb 16, 2022.

Commonly used brand name(s)

In the U.S.

Tigan

Available Dosage Forms:

Capsule

Therapeutic Class: Antiemetic

Pharmacologic Class: Anticholinergic

Uses for trimethobenzamide

Trimethobenzamide is used to treat nausea and vomiting after surgery. It is also used to treat nausea caused by gastroenteritis.

Trimethobenzamide is available only with your doctor's prescription.

Before using trimethobenzamide

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For trimethobenzamide, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to trimethobenzamide or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Because of trimethobenzamide's toxicity, use in children is not recommended. Safety and efficacy have not been established.

Geriatric

Appropriate studies on the relationship of age to the effects of trimethobenzamide have not been performed in the geriatric population. However, elderly patients are more likely to have unwanted side effects and age-related kidney disease, which may require an adjustment in the dose for patients receiving trimethobenzamide.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking trimethobenzamide, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using trimethobenzamide with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Bromopride
Potassium Citrate

Using trimethobenzamide with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Quetiapine

Interactions with food/tobacco/alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Trimethobenzamide