TriOxin Ear Drops

Generic name: chloroxylenol, benzocaine and hydrocortisone acetate
Dosage form: otic suspension
Drug class:Otic steroids with anti-infectives

Medically reviewed by Drugs.com. Last updated on May 23, 2022.

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Rx Only

TriOxin Ear Drops Description

Each 1 mL for otic administration contains:

Chloroxylenol . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 mg

Benzocaine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15 mg

Hydrocortisone Acetate . . . . . . . . . . . . . . . . . . . . . . . . . . 10 mg

INACTIVE INGREDIENTS: PEG-12 Glyceryl Dimyristate, Sodium Hydroxide, PEG-40 HCO, Purified Water, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Xanthan Gum, Potassium Sorbate, Isopropyl Alcohol.

CLINICAL PHARMACOLOGY1

TriOxin is effective both as an antibacterial and antifungal agent. The unique Hydrophilic Lipid based delivery system provides a suspension having an acid pH and a low surface tension, exerting a drying effect and allowing the medication to spread quickly to all contiguous surfaces, softening and reducing accumulated cerumen. Chloroxylenol is a halogenated phenol; non-toxic, non-corrosive, non-staining with high phenol coefficient. It may be applied directly to a wound and shows no chemical reactivity toward blood. TriOxin which contains hydrocortisone acetate is indicated when otitis is complicated by inflammation or to control itching. Benzocaine is a topical anesthetic with a low index of sensitization and toxicity.

1

van Asperen IA, de Rover CM, Schijven JF, et al. Risk of otitis externa after swimming in recreational fresh water lakes containing Pseudomonas aeruginosa. BMJ.1995;311:1407-1410.
Sander R. Otitis Externa: A Practical Guide to Treatment and Prevention. Available at http://www.aafp.org/afp/20010301/927.html. Accessed 4/9/09.
BioZone Laboratories, Inc. Qusomes™. Available at: http://www.biozonelabs.com/html/qusomes/qusomes.htm. Accessed 4/15/09.